{"id":209163,"date":"2024-12-07T13:13:22","date_gmt":"2024-12-07T13:13:22","guid":{"rendered":"https:\/\/namso-gen.co\/blog\/is-fdr-the-same-as-adjusted-p-value\/"},"modified":"2024-12-07T13:13:22","modified_gmt":"2024-12-07T13:13:22","slug":"is-fdr-the-same-as-adjusted-p-value","status":"publish","type":"post","link":"https:\/\/namso-gen.co\/blog\/is-fdr-the-same-as-adjusted-p-value\/","title":{"rendered":"Is FDR the same as adjusted p-value?"},"content":{"rendered":"<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_62 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title \" >Table of Contents<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/namso-gen.co\/blog\/is-fdr-the-same-as-adjusted-p-value\/#Is_FDR_the_same_as_adjusted_p-value\" title=\"Is FDR the same as adjusted p-value?\">Is FDR the same as adjusted p-value?<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/namso-gen.co\/blog\/is-fdr-the-same-as-adjusted-p-value\/#FAQs\" title=\"FAQs\">FAQs<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/namso-gen.co\/blog\/is-fdr-the-same-as-adjusted-p-value\/#1_What_is_the_purpose_of_adjusting_p-values\" title=\"1. What is the purpose of adjusting p-values?\">1. What is the purpose of adjusting p-values?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/namso-gen.co\/blog\/is-fdr-the-same-as-adjusted-p-value\/#2_How_is_the_Bonferroni_correction_used_to_adjust_p-values\" title=\"2. How is the Bonferroni correction used to adjust p-values?\">2. How is the Bonferroni correction used to adjust p-values?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/namso-gen.co\/blog\/is-fdr-the-same-as-adjusted-p-value\/#3_What_is_the_Holm-Bonferroni_method\" title=\"3. What is the Holm-Bonferroni method?\">3. What is the Holm-Bonferroni method?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/namso-gen.co\/blog\/is-fdr-the-same-as-adjusted-p-value\/#4_How_does_the_Benjamini-Hochberg_procedure_work\" title=\"4. How does the Benjamini-Hochberg procedure work?\">4. How does the Benjamini-Hochberg procedure work?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/namso-gen.co\/blog\/is-fdr-the-same-as-adjusted-p-value\/#5_Can_FDR_be_used_in_place_of_adjusted_p-values\" title=\"5. Can FDR be used in place of adjusted p-values?\">5. Can FDR be used in place of adjusted p-values?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/namso-gen.co\/blog\/is-fdr-the-same-as-adjusted-p-value\/#6_How_is_FDR_calculated\" title=\"6. How is FDR calculated?\">6. How is FDR calculated?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/namso-gen.co\/blog\/is-fdr-the-same-as-adjusted-p-value\/#7_What_is_the_difference_between_FWER_and_FDR\" title=\"7. What is the difference between FWER and FDR?\">7. What is the difference between FWER and FDR?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/namso-gen.co\/blog\/is-fdr-the-same-as-adjusted-p-value\/#8_When_should_FDR_be_used_over_FWER\" title=\"8. When should FDR be used over FWER?\">8. When should FDR be used over FWER?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-11\" href=\"https:\/\/namso-gen.co\/blog\/is-fdr-the-same-as-adjusted-p-value\/#9_Are_adjusted_p-values_always_more_stringent_than_unadjusted_p-values\" title=\"9. Are adjusted p-values always more stringent than unadjusted p-values?\">9. Are adjusted p-values always more stringent than unadjusted p-values?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-12\" href=\"https:\/\/namso-gen.co\/blog\/is-fdr-the-same-as-adjusted-p-value\/#10_Can_adjusted_p-values_ever_be_less_stringent_than_unadjusted_p-values\" title=\"10. Can adjusted p-values ever be less stringent than unadjusted p-values?\">10. Can adjusted p-values ever be less stringent than unadjusted p-values?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-13\" href=\"https:\/\/namso-gen.co\/blog\/is-fdr-the-same-as-adjusted-p-value\/#11_How_does_the_choice_of_significance_level_impact_adjusted_p-values\" title=\"11. How does the choice of significance level impact adjusted p-values?\">11. How does the choice of significance level impact adjusted p-values?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-14\" href=\"https:\/\/namso-gen.co\/blog\/is-fdr-the-same-as-adjusted-p-value\/#12_What_are_some_limitations_of_using_FDR_in_statistical_analysis\" title=\"12. What are some limitations of using FDR in statistical analysis?\">12. What are some limitations of using FDR in statistical analysis?<\/a><\/li><\/ul><\/li><\/ul><\/nav><\/div>\n<h2><span class=\"ez-toc-section\" id=\"Is_FDR_the_same_as_adjusted_p-value\"><\/span>Is FDR the same as adjusted p-value?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>When it comes to statistical analysis, false discovery rate (FDR) and adjusted p-values are often used interchangeably. However, they are not the same thing. While adjusted p-values control the familywise error rate (FWER), FDR controls the proportion of false positives among significant results.<\/p>\n<p>Adjusted p-values are calculated using various methods such as Bonferroni correction, Holm-Bonferroni method, and Benjamini-Hochberg procedure. These methods help to account for multiple testing and reduce the likelihood of false positives.<\/p>\n<p>On the other hand, FDR is a statistical method that aims to control the rate of false discoveries among all discoveries. It is often used in high-dimensional data analysis, such as in genomics or neuroimaging studies.<\/p>\n<h3><span class=\"ez-toc-section\" id=\"FAQs\"><\/span>FAQs<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<h3><span class=\"ez-toc-section\" id=\"1_What_is_the_purpose_of_adjusting_p-values\"><\/span>1. What is the purpose of adjusting p-values?<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\nAdjusting p-values is essential when conducting multiple hypothesis tests simultaneously to reduce the likelihood of making false discoveries.<\/p>\n<h3><span class=\"ez-toc-section\" id=\"2_How_is_the_Bonferroni_correction_used_to_adjust_p-values\"><\/span>2. How is the Bonferroni correction used to adjust p-values?<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\nThe Bonferroni correction involves dividing the desired alpha level by the number of tests being conducted to determine a more stringent significance threshold for each test.<\/p>\n<h3><span class=\"ez-toc-section\" id=\"3_What_is_the_Holm-Bonferroni_method\"><\/span>3. What is the Holm-Bonferroni method?<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\nThe Holm-Bonferroni method is a step-down procedure that adjusts p-values by sequentially comparing them to a descending threshold to control the familywise error rate.<\/p>\n<h3><span class=\"ez-toc-section\" id=\"4_How_does_the_Benjamini-Hochberg_procedure_work\"><\/span>4. How does the Benjamini-Hochberg procedure work?<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\nThe Benjamini-Hochberg procedure controls the false discovery rate by ranking p-values, determining a critical value based on a specified FDR level, and then adjusting the p-values accordingly.<\/p>\n<h3><span class=\"ez-toc-section\" id=\"5_Can_FDR_be_used_in_place_of_adjusted_p-values\"><\/span>5. Can FDR be used in place of adjusted p-values?<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\nFDR and adjusted p-values serve different purposes, but in some cases, FDR can be used as a more flexible alternative to adjust for multiple testing without being as conservative as traditional methods.<\/p>\n<h3><span class=\"ez-toc-section\" id=\"6_How_is_FDR_calculated\"><\/span>6. How is FDR calculated?<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\nFDR is calculated by determining the proportion of false positives among statistically significant results, typically using the Benjamini-Hochberg procedure.<\/p>\n<h3><span class=\"ez-toc-section\" id=\"7_What_is_the_difference_between_FWER_and_FDR\"><\/span>7. What is the difference between FWER and FDR?<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\nFamilywise error rate (FWER) controls the probability of making one or more false discoveries, while false discovery rate (FDR) controls the proportion of false positives among significant results.<\/p>\n<h3><span class=\"ez-toc-section\" id=\"8_When_should_FDR_be_used_over_FWER\"><\/span>8. When should FDR be used over FWER?<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\nFDR is more suitable when researchers are willing to tolerate a higher rate of false discoveries in exchange for greater statistical power and flexibility in hypothesis testing.<\/p>\n<h3><span class=\"ez-toc-section\" id=\"9_Are_adjusted_p-values_always_more_stringent_than_unadjusted_p-values\"><\/span>9. Are adjusted p-values always more stringent than unadjusted p-values?<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\nAdjusted p-values are typically more stringent than unadjusted p-values due to the correction for multiple comparisons, which reduces the likelihood of false positives.<\/p>\n<h3><span class=\"ez-toc-section\" id=\"10_Can_adjusted_p-values_ever_be_less_stringent_than_unadjusted_p-values\"><\/span>10. Can adjusted p-values ever be less stringent than unadjusted p-values?<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\nIn certain scenarios where the correction for multiple testing is overly conservative, adjusted p-values may be less stringent than unadjusted p-values, leading to a higher false positive rate.<\/p>\n<h3><span class=\"ez-toc-section\" id=\"11_How_does_the_choice_of_significance_level_impact_adjusted_p-values\"><\/span>11. How does the choice of significance level impact adjusted p-values?<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\nThe choice of significance level affects the stringency of adjusted p-values, with a lower alpha level resulting in more stringent adjustments to control for false discoveries.<\/p>\n<h3><span class=\"ez-toc-section\" id=\"12_What_are_some_limitations_of_using_FDR_in_statistical_analysis\"><\/span>12. What are some limitations of using FDR in statistical analysis?<span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p>\nOne limitation of using FDR is that it may lead to an increased rate of false discoveries compared to FWER methods, especially in cases where the underlying assumptions are violated.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Is FDR the same as adjusted p-value? When it comes to statistical analysis, false discovery rate (FDR) and adjusted p-values are often used interchangeably. However, they are not the same thing. While adjusted p-values control the familywise error rate (FWER), FDR controls the proportion of false positives among significant results. Adjusted p-values are calculated using &#8230; <\/p>\n<p class=\"read-more-container\"><a title=\"Is FDR the same as adjusted p-value?\" class=\"read-more button\" href=\"https:\/\/namso-gen.co\/blog\/is-fdr-the-same-as-adjusted-p-value\/#more-209163\">Read more<span class=\"screen-reader-text\">Is FDR the same as adjusted p-value?<\/span><\/a><\/p>\n","protected":false},"author":53,"featured_media":107420,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[86279],"tags":[],"class_list":["post-209163","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-learn","no-featured-image-padding"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Is FDR the same as adjusted p-value?<\/title>\n<meta name=\"description\" content=\"Is FDR the same as adjusted p-value? 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